Imaging of Ions and Metabolites in Cellular Physiology and Pathophysiology
Guest Editor : Raul Martinez-Zaguilan
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The advent of powerful optical and spectroscopic approaches has allowed the study of ions movements inside of living cells and tissues with superb spatial, spectral and temporal resolution. Fluorescent probes have been extremely useful to unravel the dynamic of ion, metabolites and signaling molecules in the signal transduction pathway leading to cellular activation following agonist/antagonist treatment. These techniques and approaches have allowed us to study cellular dynamics in many cell types. This theme will illustrate the principles and applications of these methodological innovations to the study of cell function in secretory cells, excitation contraction coupling and angiogenesis under both normal and pathological conditions. Evaluation of cellular dynamics in living cells and discrete cellular compartments and organelles will be discussed.
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